The idea of allowing egg cells to mature in the ovary to produce offspring has been implemented in various ways. One of these methods, ovarian transplantation, is a relatively simple procedure for obt...
The “Switching Off and On” of the X Chromosome is Crucial for Egg Cell Development
Researchers at the Center for Genomic Regulation (CRG) in Barcelona have identified a potential new diagnostic marker that predicts the successful and efficient development of mammalian oocytes. The r...
Scientists Discover New Approach to Rejuvenating Aged Oocytes
A research scientist at the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) and the NUS Bia-Echo Asia Centre for Reproductive Longevity and Equality (ACRLE) at the NUS Yon...
New Treatment Extends Ovarian Function in Older Mice
A woman's ovaries are like a factory where egg cells grow and produce hormones that regulate everything from menstruation and pregnancy to bone density and mood. As she and her factory age, production...
Study on Fruit Flies Could Benefit Egg Cells of Older Women
A new study conducted on fruit flies provides the first evidence that oocytes - the cells that give rise to eggs - regularly rejuvenate the critical protein bonds that hold chromosomes together. The f...
Atlas of the Human Ovary With Resolution at Cell Level is a Step Towards an Artificial Ovary
Most human eggs never have the chance to mature into eggs, a recent study sheds light on why. A new "atlas" of the human ovary provides insights that could lead to treatments that restore ovarian horm...
Researchers Discover Protein Interactions that Control Fertility in Female Mice
Researchers at the Francis Crick Institute have shed light on the proteins that control ovarian development in mice before and after birth. This could lead to a better understanding of the cause of fe...
New Discovery Reveals How the Egg Controls Sperm Entry
After the egg cell has been fertilized by a sperm, the surrounding egg shell tightens and thus mechanically prevents the penetration of further sperm and the associated death of the embryo. This is ac...
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